Research has strongly implicated cellular oxidative damage caused by free radicals. What makes alpha-lipoic acid so effective as an antioxidant is its ability to quench free radicals in both aqueous and lipid environments
Alpha-lipoic acid also is a cofactor for some of the key enzymes (alpha keto acid dehydrogenases) involved in generating energy from food and oxygen in mitochondria8-10 and thus plays a critical role in energy production within the cell’s mitochondria
One of the most beneficial effects of alpha-lipoic acid is its ability to regenerate other essential antioxidants such as vitamins C and E, coenzyme Q10, and glutathione, and the activities of superoxide dismutase (SOD) and glutathione peroxidase (GPx)
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